2021
Wagner S, Thierbach K, Zerjatke T, Glauche I, Roeder I, Scherf N
TraCurate: Efficiently curating cell tracks
SoftwareX 13, 2021, 100656, DOI Link
2020
Thielecke L, Cornils K, Glauche I
genBaRcode: a comprehensive R-package for genetic barcode analysis
Bioinformatics 36(7) 2020, 2189-2194, DOI Link
Gottschalk A, Glauche I, Cicconi S, Clark RE, Roeder I
Molecular monitoring during dose reduction predicts recurrence after TKI cessation in CML.
Blood 135(10) 2020, 766-769, DOI Link
Roeder I, Glauche I
Overlooking the obvious? On the potential of treatment alterations to predict patient-specific therapy response.
Experimental hematology 94, 2020, 26-30, DOI Link
Hoffmann K, Cazemier K, Baldow C, Schuster S, Kheifetz Y, Schirm S, Horn M, Ernst T, Volgmann C, Thiede C, Hochhaus A, Bornhäuser M, Suttorp M, Scholz M, Glauche I, Loeffler M, Roeder I
Integration of mathematical model predictions into routine workflows to support clinical decision making in haematology.
BMC medical informatics and decision making 20(1) 2020, 28, DOI Link
Hähnel T, Baldow C, Guilhot J, Guilhot F, Saussele S, Mustjoki S, Jilg S, Jost PJ, Dulucq S, Mahon FX, Roeder I, Fassoni AC, Glauche I
Model-based inference and classification of immunological control mechanisms from TKI cessation and dose reduction in CML patients.
Cancer research 80(11) 2020, 2394-2406, DOI Link
Machova Polakova K, Zizkova H, Zuna J, Motlova E, Hovorkova L, Gottschalk A, Glauche I, Koblihova J, Pecherkova P, Klamova H, Stastna Markova M, Srbova D, Benesova A, Polivkova V, Jurcek T, Zackova D, Mayer J, Ernst T, Mahon FX, Saussele S, Roeder I, Cross NCP, Hochhaus A
Analysis of chronic myeloid leukaemia during deep molecular response by genomic PCR: a traffic light stratification model with impact on treatment-free remission.
Leukemia 34(8) 2020, 2113-2124, DOI Link
Hoffmann H, Thiede C, Glauche I, Bornhaeuser M, Roeder I
Differential response to cytotoxic therapy explains treatment dynamics of acute myeloid leukaemia patients: insights from a mathematical modelling approach.
Journal of the Royal Society, Interface 17(170) 2020, 20200091, DOI Link
Morcos MNF, Zerjatke T, Glauche I, Munz CM, Ge Y, Petzold A, Reinhardt S, Dahl A, Anstee NS, Bogeska R, Milsom MD, Säwén P, Wan H, Bryder D, Roers A, Gerbaulet A
Continuous mitotic activity of primitive hematopoietic stem cells in adult mice.
The Journal of experimental medicine 217(6) 2020, DOI Link
Klingebiel T, Jürgens H, Glauche I, Gnekow A, Kandels D, Woessmann W, Schneider DT, Suttorp M
Registries and studies in the Society for Pediatric Oncology and Hematology (GPOH) - What contribution do they make to progress?
Klinische Padiatrie 232(3) 2020, 124-135, DOI Link
2019
Hoffmann H, Thiede C, Glauche I, Kramer M, Röllig C, Ehninger G, Bornhäuser M, Roeder I
The prognostic potential of monitoring disease dynamics in NPM1-positive acute myeloid leukemia
Leukemia 33(6) 2019, 1531-1534, DOI Link
Klose M, Florian MC, Gerbaulet A, Geiger H, Glauche I
Hematopoietic Stem Cell Dynamics are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach
Stem Cells, 2019, DOI Link
Fassoni AC, Roeder I, Glauche I
To Cure or Not to Cure: Consequences of Immunological Interactions in CML Treatment
Bulletin of Mathematical Biology, 2019, 1-51, DOI Link
2018
Glauche I, Kuhn M, Baldow C, Schulze P, Rothe T, Liebscher H, Roy A, Wang X, Roeder I
Quantitative prediction of long-term molecular response in TKI-treated CML - Lessons from an imatinib versus dasatinib comparison.
Scientific Reports 8, 2018, 12330, DOI Link
Fassoni AC, Baldow C, Roeder I, Glauche I
Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: A simulation study based on phase 3 trial data
Haematologica 103(11) 2018, 1825-1834, DOI Link
Roh R, Abramowski A, Hiou-Feige H, Cornils C, Rivals R, Zougman Z, Aranyossy A, Thielecke L, Truan Z, Mermod M, Monnier Y, Prassolov V, Glauche I, Nowrouzi A, Abdollahi A, Fehse B, Simon C, Tolstonog G
Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma.
Cell Rep 25(8) 2018, 2208-2222, DOI Link
Lyne A, Kent D, Laurenti E, Cornils K, Glauche I, Perié L
A track of the clones: new developments in cellular barcoding.
Experimental Hematology 68, 2018, 15-20, DOI Link
Florian C, Klose M, Sacma M, Jablanovic J, Knudson L, Nattamai K, Marka G, Vollmer A, Soller K, Sakk V, Cabezas-Wallscheid N, Zheng Y, Mulaw M, Glauche I, Geiger H
Aging alters the epigenetic asymmetry of HSC division.
PLoS Biology 16, 2018, DOI Link
Suttorp M, Schulze P, Glauche I, Göhring G, von Neuhoff N, Metzler M, Sedlacek P, de Bont E, Balduzzi A, Lausen B, Aleinikova O, Sufliarska S, Henze G, Strauss G, Eggert A, Kremens B, Groll A, Berthold F, Klein C, Groß-Wieltsch U, Sykora K, Borkhardt A, Kulozik A, Schrappe M, Nowasz C, Krumbholz M, Tauer J, Claviez A, Harbott J, Kreipe H, Schlegelberger B, Thiede C
Front-line imatinib treatment in children and adolescents with chronic myeloid leukemia: results from a phase III trial.
Leukemia 32, 2018, 1657-1669, DOI Link
Grinenko T, Eugster A, Thielecke L, Ramasz B, Krüger A, Dietz S, Glauche I, Gerbaulet A, von Bonin M, Basak O, Clevers H, Chavakis T, Wielockx B
Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice
Nature Communications 9, 2018, 1898, DOI Link
Große J, Hornstein H, Manuwald U, Kugler J, Glauche I, Rothe U
Incidence of Diabetic Ketoacidosis of New-Onset Type 1 Diabetes in Children and Adolescents in Different Countries Correlates with Human Development Index (HDI): An Updated Systematic Review, Meta-Analysis, and Meta-Regression
Hormone and Metabolic Research 03, 2018, 209-22, DOI Link
2017
Proschmann R, Baldow C, Rothe T, Suttorp M, Thiede C, Tauer JT, Müller MC, Hochhaus A, Roeder I, Glauche I
Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy.
Haematologica 102(2) 2017, e39-e42, DOI Link
Chacón-Martínez CA, Klose M, Niemann C, Glauche I, Wickström SA
Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny.
The EMBO journal 36(2) 2017, 151-164, DOI Link
Thielecke L, Aranyossy T, Dahl A, Tiwari R, Roeder I, Geiger H, Fehse B, Glauche I, Cornils K
Limitations and challenges of genetic barcode quantification
Scientific Reports 7(43249) 2017, DOI Link
Zerjatke T, Gak IA, Kirova D, Fuhrmann M, Daniel K, Gonciarz M, Müller D, Glauche I, Mansfeld J
Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification
Cell Rep. 19(9) 2017, 1953-66, DOI Link
Cornils K, Thielecke L, Winkelmann D, Aranyossy T, Lesche M, Dahl A, Roeder I, Fehse B, Glauche I
Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion
Mol Cancer 16:120(1) 2017, 1-12, DOI Link
Aranyossy T, Thielecke L, Glauche I, Fehse B, Cornils K
Genetic barcodes facilitate competitive clonal analyses in vivo
Hum Gene Ther., 2017, 1-38, DOI Link
Baldow C, Salentin S, Schroeder M, Roeder I, Glauche I
MAGPIE: Simplifying access and execution of computational models in the life sciences
PLOS Computational Biology 13(12) 2017, 1-11, DOI Link
2016
Roeder I, Scholz M, Glauche I
Systemmedizinische Ansätze in Hämatologie und Onkologie
Spectrum Onkologie 06, 2016, 50-52
Baldow C, Thielecke L, Glauche I
Model Based Analysis of Clonal Developments Allows for Early Detection of Monoclonal Conversion and Leukemia
PLoS ONE 11(10) 2016, e0165129, DOI Link
Glauche I, Scholz M, Löffler M, Roeder I
durch simulation zur optimierten therapie - e:Med-Demonstrator-Projekt HaematoOPT erarbeitet Strategien fuer modellbasierte Optimierung haematologischer Therapien
systembiologie.de 11, 2016, 78-82
Herberg M, Glauche I, Zerjatke T, Winzi M, Buchholz F, Roeder I
Dissecting mechanisms of mouse embryonic stem cells heterogeneity through a model-based analysis of transcription factor dynamics.
Journal of the Royal Society, Interface 13(117) 2016, 1-10, DOI Link
Herrmann J, Hentschel A, Glauche I, Vollmer A, Schlegel KA, Lutz R
Implant survival and patient satisfaction of reduced diameter implants made from a titanium-zirconium alloy: A retrospective cohort study with 550 implants in 311 patients.
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 44(12) 2016, 1940-44, DOI Link
Thierbach K, Shah G, Glauche I, Huisken J, Roeder I, Scherf N
Biology-inspired visualization of morphogenetic motion in the zebrafish endoderm In: IEEE: Conference Proceedings : 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)
, 978-1-4799-2349-6
2015
Niederberger T, Failmezger H, Uskat D, Poron D, Glauche I, Scherf N, Roeder I, Schroeder T, Tresch A
Factor graph analysis of live cell imaging data reveals mechanisms of cell fate decisions.
Bioinformatics (Oxford, England) , 2015, , DOI Link
Hentschel A, Herrmann J, Glauche I, Vollmer A, Schlegel KA, Lutz R
Survival and patient satisfaction of short implants during the first 2 years of function: a retrospective cohort study with 694 implants in 416 patients.
Clinical oral implants research , 2015, , DOI Link
Herberg M, Zerjatke T, de Back W, Glauche I, Roeder I
Image-based quantification and mathematical modeling of spatial heterogeneity in ESC colonies.
Cytometry. Part A : the journal of the International Society for Analytical Cytology , 2015, , DOI Link
Tauer JT, Hofbauer LC, Jung R, Gerdes S, Glauche I, Erben RG, Suttorp M
Impact of long-term exposure to the tyrosine kinase inhibitor imatinib on the skeleton of growing rats.
PloS one 10(6) 2015, e0131192, DOI Link
Gurrea Salas D, Glauche I, Tauer JT, Thiede C, Suttorp M
Can prognostic scoring systems for chronic myeloid leukemia as established in adults be applied to pediatric patients?
Annals of hematology 94(8) 2015, 1363-71, DOI Link
2014
Tauer JT, Ulmer A, Glauche I, Jung R, Suttorp M
Long-term imatinib treatment does not cause testicular toxicity in male adolescents with chronic myeloid leukemia and in a juvenile rat model.
Klinische Pädiatrie 226(3) 2014, 169-74, DOI Link
Glauche I, Baldow Ch, Fröhlich S, Schulze P, Roy A, Subar M, Wang X, Roeder I
Model-Based Characterization of the Molecular Response Dynamics of Tyrosine Kinase Inhibitor (TKI)-Treated CML Patients a Comparison of Imatinib and Dasatinib First-Line Therapy
Blood 124, 2014, 4562
Cornils K, Thielecke L, Hüser S, Forgber M, Thomaschewski M, Kleist N, Hussein K, Riecken K, Volz T, Gerdes S, Glauche I, Dahl A, Dandri M, Roeder I, Fehse B
Multiplexing clonality: combining RGB marking and genetic barcoding.
Nucleic acids research, 2014, , DOI Link
Herberg M, Kalkan T, Glauche I, Smith A, Roeder I
A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs.
PloS one 9(3) 2014, e92496, DOI Link
Bach E, Zerjatke T, Herklotz M, Scherf N, Niederwieser D, Roeder I, Pompe T, Cross M, Glauche I
Elucidating functional heterogeneity in hematopoietic progenitor cells: a combined experimental and modeling approach.
Experimental hematology 42(9) 2014, 826-37.e1-17, DOI Link
Glauche I, Roeder I
in silico hematology
Systembiologie.de 42(9) 2014, 19
2013
Scherf N, Kunze M, Thierbach K, Zerjatke T, Burek P, Herre H, Glauche I, Roeder I
Assisting the Machine Paradigms for Human-Machine Interaction in Single Cell Tracking In: Hans-Peter Meinzer, Thomas Martin Deserno, Heinz Handels, Thomas Tolxdorff (eds.): Bildverarbeitung für die Medizin 2013
Springer , 978-3-642-36479-2 (Print) 978-3-642-36480-8 (Online)
Cornils K, Bartholomae CC, Thielecke L, Lange C, Arens A, Glauche I, Mock U, Riecken K, Gerdes S, von Kalle C, Schmidt M, Roeder I, Fehse B
Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or gamma-retroviral LTR vector.
Experimental hematology 41(1) 2013, 28-38.e3, DOI Link
Horn M, Glauche I, Müller MC, Hehlmann R, Hochhaus A, Loeffler M, Roeder I
Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia.
Blood 121(2) 2013, 378-84, DOI Link
Glauche I, Bystrykh L, Eaves C, Roeder I
Stem cell clonality - Theoretical concepts, experimental techniques, and clinical challenges.
Blood cells, molecules&diseases , 2013, , DOI Link
Ulmer A, Tabea Tauer J, Glauche I, Jung R, Suttorp M
TK Inhibitor Treatment Disrupts Growth Hormone Axis: Clinical Observations in Children with CML and Experimental Data from a Juvenile Animal Model.
Klinische Padiatrie 225(3) 2013, 120-126, DOI Link
Scherf N, Ludborzs C, Thierbach K, Glauche I, Roeder I
A Fluid Registration Approach to Cell Tracking
Current Medical Imaging Reviews 9, 2013, 102-12
Gerdes S, Newrzela S, Glauche I, von Laer D, Hansmann ML, Roeder I
Mathematical modeling of oncogenesis control in mature T-cell populations.
Frontiers in immunology 4, 2013, 380, DOI Link
Scherf N, Zerjatke T, Klemm K, Glauche I, Roeder I
Beyond Genealogies: Mutual information of causal paths to analyse single cell tracking data In: IEEE: 10th International Symposium on Biomedical Imaging: From Nano to Macro, San Francisco, CA, USA, April 7-11, 2013
, 978-1-4673-6454-6/13
2012
Glauche I, Horn K, Horn M, Thielecke L, Essers MA, Trumpp A, Roeder I
Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations.
British journal of cancer 106(11) 2012, 1742-52, DOI Link
Scherf N, Franke K, Glauche I, Kurth I, Bornhäuser M, Werner C, Pompe T, Roeder I
On the symmetry of siblings: automated single-cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup.
Experimental hematology 40(2) 2012, 119-130.e9, DOI Link
Scherf N, Herberg M, Thierbach K, Zerjatke T, Kalkan T, Humphreys P, Smith A, Glauche I, Roeder I
Imaging, quantification and visualization of spatio-temporal patterning in mESC colonies under different culture conditions.
Bioinformatics (Oxford, England) 28(18) 2012, i556-i561, DOI Link
Scherf N, Ludborzs Ch, Kuska JP, Braumann UD, Scheibe P, Pompe T, Glauche I, Roeder I
FluidTracks - Combining Nonlinear Image Registration and Active Contours for Cell Tracking In: Tolxdorff, Th.; Deserno, Th.M.; Handels, H.; Meinzer, H.-P. (Hrsg.): Proc. Bildverarbeitung für die Medizin 2012
Springer , 978-3-643-28502-8
2011
Glauche I., Roeder I.
Heterogeneity and Flexibility of Stem Cell Fate Decisions â?? A Conceptual Perspective In: Michal K. Stachowiak & Emmanuel S. Tzanakakis (Eds.): Stem Cells: From Mechanisms to Technologies
World Scientific Publishing Co , 978-9814317702
Roeder I, Loeffler M, Glauche I
Towards a quantitative understanding of stem cell-niche interaction: Experiments, models, and technologies.
Blood cells, molecules & diseases 46(4) 2011, 308-17, DOI Link
Meinhardt A, Spicher A, Roehrich ME, Glauche I, Vogt P, Vassalli G
Immunohistochemical and flow cytometric analysis of long-term label-retaining cells in the adult heart.
Stem cells and development 20(2) 2011, 211-22, DOI Link
Glauche I, Thielecke L, Roeder I
Cellular aging leads to functional heterogeneity of hematopoietic stem cells: a modeling perspective.
Aging cell 10(3) 2011, 457-65, DOI Link
2010
Glauche I, Herberg M, Roeder I
Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.
PLoS one 5(6) 2010, e11238, DOI Link
Glauche I
Theoretical studies on the lineage specification of hematopoietic stem cells
PhD thesis (2010) Universität Leipzig
Burek P, Herre H, Roeder I, Glauche I, Scherf N, Loeffler M
Towards a Cellular Genealogy Ontology In: H. Herre, R. Hoehndorf, J. Kelso, S. Schulz (eds.): 2nd Workshop of the GI-Fachgruppe "Ontologien in Biomedizin und Lebenswissenschaften (OBML)", 09-10. September 2010 in Mannheim, Germany 
Universität Leipzig , ISSN 1610-7233
2009
Glauche I, Moore K, Thielecke L, Horn K, Loeffler M, Roeder I
Stem cell proliferation and quiescence--two sides of the same coin.
PLoS computational biology 5(7) 2009, e1000447, DOI Link
Glauche I, Lorenz R, Hasenclever D, Roeder I
A novel view on stem cell development: analysing the shape of cellular genealogies.
Cell proliferation 42(2) 2009, 248-63, DOI Link
2008
Roeder I, Glauche I
Pathogenesis, treatment effects, and resistance dynamics in chronic myeloid leukemia--insights from mathematical model analyses.
Journal of molecular medicine (Berlin, Germany) 86(1) 2008, 17-27, DOI Link
Scherf N, Roeder I, Glauche I
Correlation patterns of cellular genealogies In: Miika Ahdesmäki, Korbinian Strimmer, Nicole Radde, Jörg Rahnenführer, Konstantin Klemm, Harri Lähdesmäki, Olli Yli-Harja (eds.): Proccedings of the Fifth International Workshop on Computational Systems Biology (WCSB), June 11-13 2008, Leipzig, Germany
Tampere International Center for Signal Processing 41, 978-952-15-1988-8
2007
Glauche I, Horn M, Roeder I
Leukaemia stem cells: hit or miss?
British Journal of Cancer 96(4) 2007, 677-9, DOI Link
Glauche I, Cross M, Loeffler M, Roeder I
Lineage specification of hematopoietic stem cells: mathematical modeling and biological implications.
Stem cells (Dayton, Ohio) 25(7) 2007, 1791-9, DOI Link
Kuhnt M, Glauche I, Greiner M
Impact of observational incompleteness on the structural properties of protein interaction networks
Physica A-Statistical Mechanics and its Applications 373, 2007, 759-69, DOI Link
2006
Roeder I, Horn M, Glauche I, Hochhaus A, Mueller MC, Loeffler M
Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications.
Nature medicine 12(10) 2006, 1181-4, DOI Link
Roeder I, Glauche I
Towards an understanding of lineage specification in hematopoietic stem cells: a mathematical model for the interaction of transcription factors GATA-1 and PU.1.
Journal of theoretical biology 241(4) 2006, 852-65, DOI Link
Sollacher R, Greiner M, Glauche I
Impact of interference on the wireless ad-hoc networks capacity and topology
Wireless Networks 12(1) 2006, 53-61, DOI Link
2004
Glauche I, Krause W, Sollacher R, Greiner M
Distributive routing and congestion control in wireless multihop ad hoc communication networks
Physica A-Statistical Mechanics and its Applications 341, 2004, 677-701, DOI Link
Krause W, Glauche I, Sollacher R, Greiner M
Impact of network structure on the capacity of wireless multihop ad hoc communication
Physica A-Statistical Mechanics and its Applications 338(3-4) 2004, 633-658, DOI Link
2003
Glauche I, Krause W, Sollacher R, Greiner M
Continuum percolation of wireless ad hoc communication networks
Physica A-Statistical Mechanics and its Applications 325(3-4) 2003, 577-600, DOI Link


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