2020
Gottschalk A, Glauche I, Cicconi S, Clark RE, Roeder I
Molecular monitoring during dose reduction predicts recurrence after TKI cessation in CML.
Blood 135(10) 2020, 766-769, DOI Link
Hoffmann K, Cazemier K, Baldow C, Schuster S, Kheifetz Y, Schirm S, Horn M, Ernst T, Volgmann C, Thiede C, Hochhaus A, Bornhäuser M, Suttorp M, Scholz M, Glauche I, Loeffler M, Roeder I
Integration of mathematical model predictions into routine workflows to support clinical decision making in haematology.
BMC medical informatics and decision making 20(1) 2020, 28, DOI Link
Hähnel T, Baldow C, Guilhot J, Guilhot F, Saussele S, Mustjoki S, Jilg S, Jost PJ, Dulucq S, Mahon FX, Roeder I, Fassoni AC, Glauche I
Model-based inference and classification of immunological control mechanisms from TKI cessation and dose reduction in CML patients.
Cancer research 80(11) 2020, 2394-2406, DOI Link
Johansson P, Klein-Hitpass L, Budeus B, Kuhn M, Lauber C, Seifert M, Roeder I, Pförtner R, Stuschke M, Dührsen U, Eckstein A, Dürig J, Küppers R
Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing.
Cancers 12(4) 2020, DOI Link
Erdmann K, Salomo K, Klimova A, Heberling U, Lohse-Fischer A, Fuehrer R, Thomas C, Roeder I, Froehner M, Wirth MP, Fuessel S
Urinary MicroRNAs as Potential Markers for Non-Invasive Diagnosis of Bladder Cancer.
International journal of molecular sciences 21(11) 2020, DOI Link
Kloenne M, Niehaus S, Lampe L, Merola A, Reinelt J, Roeder I, Scherf N
Domain-specific cues improve robustness of deep learning-based segmentation of CT volumes.
Scientific reports 10(1) 2020, 10712, DOI Link
Machova Polakova K, Zizkova H, Zuna J, Motlova E, Hovorkova L, Gottschalk A, Glauche I, Koblihova J, Pecherkova P, Klamova H, Stastna Markova M, Srbova D, Benesova A, Polivkova V, Jurcek T, Zackova D, Mayer J, Ernst T, Mahon FX, Saussele S, Roeder I, Cross NCP, Hochhaus A
Analysis of chronic myeloid leukaemia during deep molecular response by genomic PCR: a traffic light stratification model with impact on treatment-free remission.
Leukemia 34(8) 2020, 2113-2124, DOI Link
Lauber C, Correia N, Trumpp A, Rieger MA, Dolnik A, Bullinger L, Roeder I, Seifert M
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.
Scientific reports 10(1) 2020, 12761, DOI Link
Bondarieva A, Raveendran K, Telychko V, Rao HBDP, Ravindranathan R, Zorzompokou C, Finsterbusch F, Dereli I, Papanikos F, Tränkner D, Schleiffer A, Fei JF, Klimova A, Ito M, Kulkarni DS, Roeder I, Hunter N, Tóth A
Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse.
Nature communications 11(1) 2020, 3101, DOI Link
Diebner HH, Kather A, Roeder I, de With K
Mathematical basis for the assessment of antibiotic resistance and administrative counter-strategies.
PloS one 15(9) 2020, e0238692, DOI Link
Hoffmann H, Thiede C, Glauche I, Bornhaeuser M, Roeder I
Differential response to cytotoxic therapy explains treatment dynamics of acute myeloid leukaemia patients: insights from a mathematical modelling approach.
Journal of the Royal Society, Interface 17(170) 2020, 20200091, DOI Link
Oberbeck S, Schrader A, Warner K, Jungherz D, Crispatzu G, von Jan J, Chmielewski M, Ianevski A, Diebner HH, Mayer P, Kondo Ados A, Wahnschaffe L, Braun T, Müller TA, Wagle P, Bouska A, Neumann T, Pützer S, Varghese L, Pflug N, Thelen M, Makalowski J, Riet N, Göx HJM, Rappl G, Altmüller J, Kotrova M, Persigehl T, Hopfinger G, Hansmann ML, Schlößer H, Stilgenbauer S, Dürig J, Mougiakakos D, von Bergwelt-Baildon M, Roeder I, Hartmann S, Hallek M, Moriggl RH, Brüggemann M, Aittokallio T, Iqbal J, Newrzela S, Abken H, Herling M
Non-canonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling
Blood, 2020, DOI Link
2019
Seurig S, de Back W, Scherf N, Röder I
Automating pollen counting using deep learning
Allergo Journal Sep 2019, 2019
Hoffmann H, Thiede C, Glauche I, Kramer M, Röllig C, Ehninger G, Bornhäuser M, Roeder I
The prognostic potential of monitoring disease dynamics in NPM1-positive acute myeloid leukemia
Leukemia 33(6) 2019, 1531-1534, DOI Link
Fassoni AC, Roeder I, Glauche I
To Cure or Not to Cure: Consequences of Immunological Interactions in CML Treatment
Bulletin of Mathematical Biology, 2019, 1-51, DOI Link
Zakrzewski F, de Back W, Weigert M, Wenke T, Zeugner S, Mantey R, Sperling C, Friedrich K, Roeder I, Aust D, Baretton G, Hönscheid P
Automated detection of the HER2 gene amplification status in Fluorescence in situ hybridization images for the diagnostics of cancer tissues
Scientific Reports 9(8231) 2019, DOI Link
de Back W, Zerjatke T, Roeder I
Statistical and Mathematical Modeling of Spatiotemporal Dynamics of Stem Cells
Methods in Molecular Biology 2017, 2019, 219-243, DOI Link
Shah G, Thierbach K, Schmid B, Waschke J, Reade A, Hlawitschka M, Roeder I, Scherf N, Huiken J
Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish
Nature Communications 10(5753) 2019, DOI Link
Nieswald V, Richter M, Berner R, von der Hagen M, Klimova A, Roeder I, Koch T, Sabatowski R, Gossrau G
The prevalence of headache in German pupils of different ages and school types
Cephalalgia 39(8) 2019, DOI Link
2018
Glauche I, Kuhn M, Baldow C, Schulze P, Rothe T, Liebscher H, Roy A, Wang X, Roeder I
Quantitative prediction of long-term molecular response in TKI-treated CML - Lessons from an imatinib versus dasatinib comparison.
Scientific Reports 8, 2018, 12330, DOI Link
Fassoni AC, Baldow C, Roeder I, Glauche I
Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: A simulation study based on phase 3 trial data
Haematologica 103(11) 2018, 1825-1834, DOI Link
Gaspari E, Franke A, Robles-Diaz D, Zweigerdt R, Roeder I, Zerjatke T, Kempf H
Paracrine mechanisms in early differentiation of human pluripotent stem cells: Insights from a mathematical model
Stem Cell Research 32, 2018, 1-7, DOI Link
Apweiler R, Beissbarth T, Berthold MR, Blüthgen N, Burmeister Y, Dammann O, Deutsch A, Feuerhake F, Franke A, Hasenauer J, Hoffmann S, Höfer T, Jansen PLM, Kaderali L, Klingmüller U, Koch I, Kohlbacher O, Kuepfer L, Lammert F, Maier D, Pfeifer N, Radde N, Rehm M, Roeder I, Saez-Rodriguez J, Sax U, Schmeck B, Schuppert A, Seilheimer B, Theis FJ, Vera J, Wolkenhauer O
Whither systems medicine?
Experimental & Molecular Medicine 50, 2018, e453, DOI Link
Diebner HH, Zerjatke T, Griehl M, Roeder I
Metabolism is the tie: The Bertalanffy-type cancer growth model as common denominator of various modelling approaches
Biosystems 167, 2018, 1-23, DOI Link
2017
Proschmann R, Baldow C, Rothe T, Suttorp M, Thiede C, Tauer JT, Müller MC, Hochhaus A, Roeder I, Glauche I
Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy.
Haematologica 102(2) 2017, e39-e42, DOI Link
Herold S, Kuhn M, von Bonin M, Stange T, Platzbecker U, Radke J, Lange T, Sockel K, Gutsche K, Schetelig J, Röllig C, Schuster C, Roeder I, Dahl A, Mohr B, Serve H, Brandts C, Ehninger G, Bornhäuser M, Thiede C
Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient
Leukemia, 2017, DOI Link
Herling M, Rengstl B, Scholtysik R, Hartmann S, Küppers R, Hansmann ML, Diebner HH, Roeder I, Abken H, Newrzela S, Kirberg J
Concepts in mature T-cell lymphomas - highlights from an international joint symposium on T-cell immunology and oncology
Leukemia & Lymphoma 58(4) 2017, 788-796, DOI Link
Thielecke L, Aranyossy T, Dahl A, Tiwari R, Roeder I, Geiger H, Fehse B, Glauche I, Cornils K
Limitations and challenges of genetic barcode quantification
Scientific Reports 7(43249) 2017, DOI Link
Cornils K, Thielecke L, Winkelmann D, Aranyossy T, Lesche M, Dahl A, Roeder I, Fehse B, Glauche I
Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion
Mol Cancer 16:120(1) 2017, 1-12, DOI Link
Bandoła J, Richter C, Ryser M, Jamal A, Ashton MP, von Bonin M, Kuhn M, Dorschner B, Alexopoulou D, Navratiel K, Roeder I, Dahl A, Hedrich CM, Bonifacio E, Brenner S, Thieme S
Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells
Front Immunol. 8(981) 2017, 1-16, DOI Link
MacLean AL, Smith MA, Liepe J, Sim A, Khorshed R, Rashidi NM, Scherf N, Krinner A, Roeder I, Lo Celso C, Stumpf MPH
Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection
Stem Cells 35(11) 2017, 2292–2304, DOI Link
Hohenstein B, Julius U, Lansberg P, Jaeger B, Mellwig KP, Weiss N, Graehlert X, Roeder I, Ramlow W
Rationale and design of MultiSELECt: A European Multicenter Study on the Effect of Lipoprotein(a) Elimination by lipoprotein apheresis on Cardiovascular outcomes
Atherosclerosis Supplements, 2017, 180-186, DOI Link
Baldow C, Salentin S, Schroeder M, Roeder I, Glauche I
MAGPIE: Simplifying access and execution of computational models in the life sciences
PLOS Computational Biology 13(12) 2017, 1-11, DOI Link
2016
Roeder I, Scholz M, Glauche I
Systemmedizinische Ansätze in Hämatologie und Onkologie
Spectrum Onkologie 06, 2016, 50-52
Diebner HH, Marrè B, Roeder I, Walter MH
Process-based approach to modeling recurrent-event data explicated on the basis of occurrences of tooth losses in two different prosthetic treatment concepts
Trials 17(1) 2016, 244, DOI Link
Glauche I, Scholz M, Löffler M, Roeder I
durch simulation zur optimierten therapie - e:Med-Demonstrator-Projekt HaematoOPT erarbeitet Strategien fuer modellbasierte Optimierung haematologischer Therapien
systembiologie.de 11, 2016, 78-82
Kuhn M, Stange T, Herold S, Thiede C, Roeder I
Finding small somatic structural variants in exome sequencing data: a machine learning approach
Computational Statistics, 2016, 1-14, DOI Link
Herberg M, Glauche I, Zerjatke T, Winzi M, Buchholz F, Roeder I
Dissecting mechanisms of mouse embryonic stem cells heterogeneity through a model-based analysis of transcription factor dynamics.
Journal of the Royal Society, Interface 13(117) 2016, 1-10, DOI Link
Schoedel KB, Morcos MN, Zerjatke T, Roeder I, Grinenko T, Voehringer D, Göthert JR, Waskow C, Roers A, Gerbaulet A
The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis.
Blood, 2016, 1-13, DOI Link
Thierbach K, Shah G, Glauche I, Huisken J, Roeder I, Scherf N
Biology-inspired visualization of morphogenetic motion in the zebrafish endoderm In: IEEE: Conference Proceedings : 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI)
, 978-1-4799-2349-6
2015
Niederberger T, Failmezger H, Uskat D, Poron D, Glauche I, Scherf N, Roeder I, Schroeder T, Tresch A
Factor graph analysis of live cell imaging data reveals mechanisms of cell fate decisions.
Bioinformatics (Oxford, England) , 2015, , DOI Link
Herberg M, Zerjatke T, de Back W, Glauche I, Roeder I
Image-based quantification and mathematical modeling of spatial heterogeneity in ESC colonies.
Cytometry. Part A : the journal of the International Society for Analytical Cytology , 2015, , DOI Link
Chmelova H, Cohrs CM, Chouinard JA, Petzold C, Kuhn M, Chen C, Roeder I, Kretschmer K, Speier S
Distinct roles of beta cell mass and function during type 1 diabetes onset and remission.
Diabetes , 2015, , DOI Link
Garthe A, Roeder I, Kempermann G
Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis.
Hippocampus , 2015, , DOI Link
Giordano FA, Appelt JU, Link B, Gerdes S, Lehrer C, Scholz S, Paruzynski A, Roeder I, Wenz F, Glimm H, von Kalle C, Grez M, Schmidt M, Laufs S
High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies.
Molecular therapy. Methods&clinical development 2, 2015, 14061, DOI Link
Herberg M, Roeder I
Computational modelling of embryonic stem-cell fate control.
Development (Cambridge, England) 142(13) 2015, 2250-60, DOI Link
Diebner HH, Kirberg J, Roeder I
An evolutionary stability perspective on oncogenesis control in mature T-cell populations.
Journal of theoretical biology , 2015, , DOI Link
2014
Krinner A, Roeder I
Quantification and Modeling of Stem Cell-Niche Interaction In: Seth J Corey, Marek Kimmel and Joshua N. Leonard (Eds.): A Systems Biology - Approach to Blood
Springer Science+Business Media 844, 978-1-4939-2094-5
Beyer-Westendorf J, Gelbricht V, Förster K, Ebertz F, Röllig D, Schreier T, Tittl L, Thieme C, Hänsel U, Köhler C, Werth S, Kuhlisch E, Stange T, Röder I, Weiss N
Safety of switching from vitamin K antagonists to dabigatran or rivaroxaban in daily care--results from the Dresden NOAC registry.
British journal of clinical pharmacology 78(4) 2014, 908-17, DOI Link
Lützner C, Voigt H, Roeder I, Kirschner S
Placement makes a difference: Accuracy of an accelerometer in measuring step number and stair climbing.
Gait&posture, 2014, , DOI Link
Glauche I, Baldow Ch, Fröhlich S, Schulze P, Roy A, Subar M, Wang X, Roeder I
Model-Based Characterization of the Molecular Response Dynamics of Tyrosine Kinase Inhibitor (TKI)-Treated CML Patients a Comparison of Imatinib and Dasatinib First-Line Therapy
Blood 124, 2014, 4562
Knaack S, Lode A, Hoyer B, Rösen-Wolff A, Gabrielyan A, Roeder I, Gelinsky M
Heparin modification of a biomimetic bone matrix for controlled release of VEGF.
Journal of biomedical materials research. Part A 102(10) 2014, 3500-11, DOI Link
Cornils K, Thielecke L, Hüser S, Forgber M, Thomaschewski M, Kleist N, Hussein K, Riecken K, Volz T, Gerdes S, Glauche I, Dahl A, Dandri M, Roeder I, Fehse B
Multiplexing clonality: combining RGB marking and genetic barcoding.
Nucleic acids research, 2014, , DOI Link
Herberg M, Kalkan T, Glauche I, Smith A, Roeder I
A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs.
PloS one 9(3) 2014, e92496, DOI Link
Rashidi NM, Scott MK, Scherf N, Krinner A, Kalchschmidt JS, Gounaris K, Selkirk ME, Roeder I, Lo Celso C
In vivo time-lapse imaging of mouse bone marrow reveals differential niche engagement by quiescent and naturally activated hematopoietic stem cells.
Blood, 2014, , DOI Link
Bach E, Zerjatke T, Herklotz M, Scherf N, Niederwieser D, Roeder I, Pompe T, Cross M, Glauche I
Elucidating functional heterogeneity in hematopoietic progenitor cells: a combined experimental and modeling approach.
Experimental hematology 42(9) 2014, 826-37.e1-17, DOI Link
Krinner A, Roeder I
Quantification and modeling of stem cell-niche interaction.
Advances in experimental medicine and biology 844, 2014, 11-36, DOI Link
Glauche I, Roeder I
in silico hematology
Systembiologie.de 42(9) 2014, 19
2013
Scherf N, Kunze M, Thierbach K, Zerjatke T, Burek P, Herre H, Glauche I, Roeder I
Assisting the Machine Paradigms for Human-Machine Interaction in Single Cell Tracking In: Hans-Peter Meinzer, Thomas Martin Deserno, Heinz Handels, Thomas Tolxdorff (eds.): Bildverarbeitung für die Medizin 2013
Springer , 978-3-642-36479-2 (Print) 978-3-642-36480-8 (Online)
Cornils K, Bartholomae CC, Thielecke L, Lange C, Arens A, Glauche I, Mock U, Riecken K, Gerdes S, von Kalle C, Schmidt M, Roeder I, Fehse B
Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or gamma-retroviral LTR vector.
Experimental hematology 41(1) 2013, 28-38.e3, DOI Link
Horn M, Glauche I, Müller MC, Hehlmann R, Hochhaus A, Loeffler M, Roeder I
Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia.
Blood 121(2) 2013, 378-84, DOI Link
Kustikova OS, Schwarzer A, Stahlhut M, Brugman MH, Neumann T, Yang M, Li Z, Schambach A, Heinz N, Gerdes S, Roeder I, Ha TC, Steinemann D, Schlegelberger B, Baum C
Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells.
Leukemia 27(5) 2013, 1127-38, DOI Link
Glauche I, Bystrykh L, Eaves C, Roeder I
Stem cell clonality - Theoretical concepts, experimental techniques, and clinical challenges.
Blood cells, molecules&diseases , 2013, , DOI Link
Schmid B, Shah G, Scherf N, Weber M, Thierbach K, Campos CP, Roeder I, Aanstad P, Huisken J
High-speed panoramic light-sheet microscopy reveals global endodermal cell dynamics.
Nature communications 4, 2013, 2207, DOI Link
Scherf N, Ludborzs C, Thierbach K, Glauche I, Roeder I
A Fluid Registration Approach to Cell Tracking
Current Medical Imaging Reviews 9, 2013, 102-12
Krinner A, Roeder I, Loeffler M, Scholz M
Merging concepts - coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis.
BMC systems biology 7(1) 2013, 117, DOI Link
Gerdes S, Newrzela S, Glauche I, von Laer D, Hansmann ML, Roeder I
Mathematical modeling of oncogenesis control in mature T-cell populations.
Frontiers in immunology 4, 2013, 380, DOI Link
Scherf N, Zerjatke T, Klemm K, Glauche I, Roeder I
Beyond Genealogies: Mutual information of causal paths to analyse single cell tracking data In: IEEE: 10th International Symposium on Biomedical Imaging: From Nano to Macro, San Francisco, CA, USA, April 7-11, 2013
, 978-1-4673-6454-6/13
2012
Glauche I, Horn K, Horn M, Thielecke L, Essers MA, Trumpp A, Roeder I
Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations.
British journal of cancer 106(11) 2012, 1742-52, DOI Link
Scherf N, Franke K, Glauche I, Kurth I, Bornhäuser M, Werner C, Pompe T, Roeder I
On the symmetry of siblings: automated single-cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup.
Experimental hematology 40(2) 2012, 119-130.e9, DOI Link
Newrzela S, Al-Ghaili N, Heinrich T, Petkova M, Hartmann S, Rengstl B, Kumar A, Jäck HM, Gerdes S, Roeder I, Hansmann ML, von Laer D
T-cell receptor diversity prevents T-cell lymphoma development.
Leukemia 26(12) 2012, 2499-507, DOI Link
Scherf N, Herberg M, Thierbach K, Zerjatke T, Kalkan T, Humphreys P, Smith A, Glauche I, Roeder I
Imaging, quantification and visualization of spatio-temporal patterning in mESC colonies under different culture conditions.
Bioinformatics (Oxford, England) 28(18) 2012, i556-i561, DOI Link
Scherf N, Ludborzs Ch, Kuska JP, Braumann UD, Scheibe P, Pompe T, Glauche I, Roeder I
FluidTracks - Combining Nonlinear Image Registration and Active Contours for Cell Tracking In: Tolxdorff, Th.; Deserno, Th.M.; Handels, H.; Meinzer, H.-P. (Hrsg.): Proc. Bildverarbeitung für die Medizin 2012
Springer , 978-3-643-28502-8
2011
Glauche I., Roeder I.
Heterogeneity and Flexibility of Stem Cell Fate Decisions â?? A Conceptual Perspective In: Michal K. Stachowiak & Emmanuel S. Tzanakakis (Eds.): Stem Cells: From Mechanisms to Technologies
World Scientific Publishing Co , 978-9814317702
Herberg M, Roeder I
Epigenetic Nanog regulation and the role of functional heterogeneity.
Cell cycle (Georgetown, Tex.) 10(14) 2011, 1488-98
Giordano FA, Sorg UR, Appelt JU, Lachmann N, Bleier S, Roeder I, Kleff V, Flasshove M, Zeller WJ, Allgayer H, Kalle C, Fruehauf S, Moritz T, Laufs S
Clonal Inventory Screens Uncover Monoclonality Following Serial Transplantation of MGMT(P140K)-Transduced Stem Cells and Dose-Intense Chemotherapy.
Human gene therapy 22(6) 2011, 697-710, DOI Link
Roeder I, Loeffler M, Glauche I
Towards a quantitative understanding of stem cell-niche interaction: Experiments, models, and technologies.
Blood cells, molecules & diseases 46(4) 2011, 308-17, DOI Link
Glauche I, Thielecke L, Roeder I
Cellular aging leads to functional heterogeneity of hematopoietic stem cells: a modeling perspective.
Aging cell 10(3) 2011, 457-65, DOI Link
2010
Glauche I, Herberg M, Roeder I
Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.
PLoS one 5(6) 2010, e11238, DOI Link
Burek P, Herre H, Roeder I, Glauche I, Scherf N, Loeffler M
Towards a Cellular Genealogy Ontology In: H. Herre, R. Hoehndorf, J. Kelso, S. Schulz (eds.): 2nd Workshop of the GI-Fachgruppe "Ontologien in Biomedizin und Lebenswissenschaften (OBML)", 09-10. September 2010 in Mannheim, Germany 
Universität Leipzig , ISSN 1610-7233
2009
d'Inverno M, Howells P, Montagna S, Roeder I, Saunders R
Agent-Based Modeling of Stem Cells In: Adelinde M. Uhrmacher, Danny Weyns (eds.): Multi-Agent Systems
Taylor & Francis Group (CRC Press) , 978-1-4200-7023-1
Köhler C, Manteufel J, Röder I, Rösler U, Truyen U
Vergleichende Untersuchungen zur Tenazität verschiedener Modellviren gegenüber chemischen Desinfektionsmitteln (Comparative investigations on tenacity of different model viruses for testing chemical disinfectants)
Hygiene Medizin 34(6) 2009, 224-32
Roeder I, Herberg M, Horn M
An"age"-structured model of hematopoietic stem cell organization with application to chronic myeloid leukemia.
Bulletin of mathematical biology 71(3) 2009, 602-26, DOI Link
Appelt JU, Giordano FA, Ecker M, Roeder I, Grund N, Hotz-Wagenblatt A, Opelz G, Zeller WJ, Allgayer H, Fruehauf S, Laufs S
QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis.
Gene therapy 16(7) 2009, 885-93, DOI Link
Roeder I, d′Inverno M
New experimental and theoretical investigations of hematopoietic stem cells and chronic myeloid leukemia.
Blood cells, molecules & diseases 43(1) 2009, 88-97, DOI Link
Roeder I, Radtke F
Stem cell biology meets systems biology.
Development (Cambridge, England) 136(21) 2009, 3525-30, DOI Link
Glauche I, Moore K, Thielecke L, Horn K, Loeffler M, Roeder I
Stem cell proliferation and quiescence--two sides of the same coin.
PLoS computational biology 5(7) 2009, e1000447, DOI Link
Glauche I, Lorenz R, Hasenclever D, Roeder I
A novel view on stem cell development: analysing the shape of cellular genealogies.
Cell proliferation 42(2) 2009, 248-63, DOI Link
Röder I
Model-Based Analysis of Stem Cell Dynamics - An Application of Medical Systems Biology
Habilitation (2009) University of Leipzig
2008
Fehse B, Roeder I
Insertional mutagenesis and clonal dominance: biological and statistical considerations.
Gene therapy 15(2) 2008, 143-53, DOI Link
Horn M, Loeffler M, Roeder I
Mathematical modeling of genesis and treatment of chronic myeloid leukemia.
Cells, tissues, organs 188(1-2) 2008, 236-47, DOI Link
Roeder I, Horn K, Sieburg HB, Cho R, Muller-Sieburg C, Loeffler M
Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach.
Blood 112(13) 2008, 4874-83, DOI Link
Roeder I, Glauche I
Pathogenesis, treatment effects, and resistance dynamics in chronic myeloid leukemia--insights from mathematical model analyses.
Journal of molecular medicine (Berlin, Germany) 86(1) 2008, 17-27, DOI Link
Scherf N, Roeder I, Glauche I
Correlation patterns of cellular genealogies In: Miika Ahdesmäki, Korbinian Strimmer, Nicole Radde, Jörg Rahnenführer, Konstantin Klemm, Harri Lähdesmäki, Olli Yli-Harja (eds.): Proccedings of the Fifth International Workshop on Computational Systems Biology (WCSB), June 11-13 2008, Leipzig, Germany
Tampere International Center for Signal Processing 41, 978-952-15-1988-8
2007
Glauche I, Horn M, Roeder I
Leukaemia stem cells: hit or miss?
British Journal of Cancer 96(4) 2007, 677-9, DOI Link
Glauche I, Cross M, Loeffler M, Roeder I
Lineage specification of hematopoietic stem cells: mathematical modeling and biological implications.
Stem cells (Dayton, Ohio) 25(7) 2007, 1791-9, DOI Link
Bozorgmehr F, Laufs S, Sellers SE, Roeder I, Zeller WJ, Zeller WJ, Dunbar CE, Fruehauf S
No evidence of clonal dominance in primates up to 4 years following transplantation of multidrug resistance 1 retrovirally transduced long-term repopulating cells.
Stem cells (Dayton, Ohio) 25(10) 2007, 2610-8, DOI Link
Roeder I, Braesel K, Lorenz R, Loeffler M
Stem cell fate analysis revisited: interpretation of individual clone dynamics in the light of a new paradigm of stem cell organization.
Journal of biomedicine&biotechnology 2007(3) 2007, 84656, DOI Link
2006
Roeder I, Galle J, Loeffler M
Theoretical Concepts of Tissue Stem-Cell Organization In: Christopher S. Potten, Robert B. Clarke, James Wilson, Andrew Renehan: Tissue stem cells
Taylor & Francis Group (CRC Press) , 0-8247-2899-8
Kirkland MA, Quesenberry PJ, Roeder I
Discrete stem cells: subsets or a continuum?
Blood 108(12) 2006, 3949; author reply 3950, DOI Link
Roeder I
Quantitative stem cell biology: computational studies in the hematopoietic system.
Current opinion in hematology 13(4) 2006, 222-8, DOI Link
Roeder I, Horn M, Glauche I, Hochhaus A, Mueller MC, Loeffler M
Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications.
Nature medicine 12(10) 2006, 1181-4, DOI Link
Roeder I, Glauche I
Towards an understanding of lineage specification in hematopoietic stem cells: a mathematical model for the interaction of transcription factors GATA-1 and PU.1.
Journal of theoretical biology 241(4) 2006, 852-65, DOI Link
Roeder I, Lorenz R
Asymmetry of stem cell fate and the potential impact of the niche: observations, simulations, and interpretations.
Stem cell reviews 2(3) 2006, 171-80, DOI Link
Roeder I
Systems stem cell biology In: Rubem P. Mondaini, Rui Dilão (eds.): BIOMAT 2006 - International Symposium on Mathematical and Computational Biology (Manaus, Brazil, 27 â?? 30 November 2006)
World Scientific Publishing Co. , 978-981-270-768-0
2005
Rupf S, Brader I, Vonderlind D, Kannengiesser S, Eschrich K, Roeder I, Merte K
In vitro, clinical, and microbiological evaluation of a linear oscillating device for scaling and root planing.
Journal of periodontology 76(11) 2005, 1942-9, DOI Link
Krohn K, Eszlinger M, Paschke R, Roeder I, Schuster E
Increased power of microarray analysis by use of an algorithm based on a multivariate procedure.
Bioinformatics (Oxford, England) 21(17) 2005, 3530-4, DOI Link
Roeder I, Kamminga LM, Braesel K, Dontje B, de Haan G, Loeffler M
Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization.
Blood 105(2) 2005, 609-16, DOI Link
2004
Roeder I, Loeffler M
Simulation of Haematopoietic Stem Cell Organisation Using a Single Cell Based Model Approach In: Andreas Deutsch, Jonathon Howard, Martin Falcke, Walter Zimmermann (eds.): Function and Regulation of Cellular systems
Birkhäuser Verlag , 3-7643-6925-6
Loeffler M, Roeder I
Conceptual models to understand tissue stem cell organization.
Current opinion in hematology 11(2) 2004, 81-7, DOI Link
Schuster E, Kropf S, Roeder I
Micro array based gene expression analysis using parametric multivariate tests per gene a generalized application of multiple procedures with data-driven order of hypotheses
Biometrical Journal 46(6) 2004, 687-98, DOI Link
2003
Roeder I, Loeffler M, Quesenberry PJ, Colvin GA, Lambert JF
Quantitative tissue stem cell modeling.
Blood 102(3) 2003, 1143-4; author reply 1144-5, DOI Link
Röder I
Dynamical Modeling of Hematopoietic Stem Cell Organization - Design and Validation of the New Concept of Within-Tissue Plasticity
PhD thesis (2003) University of Leipzig
2002
Roeder I, Loeffler M
A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity.
Experimental hematology 30(8) 2002, 853-61, DOI Link
Loeffler M, Roeder I
Tissue stem cells: definition, plasticity, heterogeneity, self-organization and models--a conceptual approach.
Cells, tissues, organs 171(1) 2002, 8-26, DOI Link
2000
Leinung S, Würl P, Schönfelder A, Weiss CL, Röder I, Schönfelder M
Detection of cytokeratin-positive cells in bone marrow in breast cancer and colorectal carcinoma in comparison with other factors of prognosis
Journal of Hematotherapy & Stem Cell Research 9(6) 2000, 905-11
Leinung S, Würl P, Schönfelder A, Weiss CL, Röder I, Schönfelder M
Detection of cytokeratin-positive cells in bone marrow in breast cancer and colorectal carcinoma in comparison with other factors of prognosis
Journal of Hematotherapy & Stem Cell Research 9(6) 2000, 905-11
Leinung S, Würl P, Schönfelder A, Weiss CL, Röder I, Schönfelder M
Rating of isolated disseminated tumor cells in bone marrow in comparison with other factors of prognosis in breast carcinoma.
Int J Surg Investig 2(3) 2000, 193-202
Leinung S, Würl P, Weiss CL, Röder I, Schönfelder M
Cytokeratin-positive cells in bone marrow in comparison with other prognostic factors in colon carcinoma
Langenbecks Archives of Surgery 385(5) 2000, 337-43
Dette H, Roeder I
Online calculation of efficient designs for multi-factor models
Biometrical Journal 42(3) 2000, 349-62
1998
Roeder I, de Haan G, Engel C, Nijhof W, Dontje B, Loeffler M
Interactions of erythropoietin, granulocyte colony-stimulating factor, stem cell factor, and interleukin-11 on murine hematopoiesis during simultaneous administration.
Blood 91(9) 1998, 3222-9, DOI Link
1997
Dette H, Röder I
Optimal discrimination designs for multifactor experiments
Annals of Statistics 25(3) 1997, 1161-75
1996
Dette H, Röder I
Optimal product designs for multivariate regression with missing terms
Scandinavian Journal of Statistics 23(2) 1996, 195-208


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