2020
Johansson P, Klein-Hitpass L, Budeus B, Kuhn M, Lauber C, Seifert M, Roeder I, Pförtner R, Stuschke M, Dührsen U, Eckstein A, Dürig J, Küppers R
Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing.
Cancers 12(4) 2020, DOI Link
Seifert M, Schackert G, Temme A, Schröck E, Deutsch A, Klink B
Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs.
Cancers 12(6) 2020, DOI Link
Lauber C, Correia N, Trumpp A, Rieger MA, Dolnik A, Bullinger L, Roeder I, Seifert M
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.
Scientific reports 10(1) 2020, 12761, DOI Link
Becker LL, Dafsari HS, Schallner J, Abdin D, Seifert M, Petit F, Smol T, Bok L, Rodan L, Krapels I, Spranger S, Weschke B, Johnson K, Straub V, Kaindl AM, Di Donato N, von der Hagen M, Cirak S
The clinical-phenotype continuum in DYNC1H1-related disorders-genomic profiling and proposal for a novel classification.
Journal of human genetics, 2020, DOI Link
2019
Lauber C, Seifert M, Bartenschlager R, Seitz S
Discovery of highly divergent lineages of plant-associated astro-like viruses sheds light on the emergence of potyviruses
Virus Research 260, 2019, 38-48, DOI Link
Liu Y, Mi Y, Mueller T, Kreibich S, Williams EG, Van Drogen A, Borel C, Frank M, Germain PL, Bludau I, Mehnert M, Seifert M, Emmenlauer M, Sorg I, Bezrukov F, Bena FS, Zhou H, Dehio C, Testa G, Saez-Rodriguez J, Antonarakis SE, Hardt WD, Aebersold R
Multi-omic measurements of heterogeneity in HeLa cells across laboratories
Nature Biotechnology, 2019, DOI Link
Zakrzewski F, Gieldon L, Rump A, Seifert M, Grützmann K, Krüger A, Loos S, Zeugner S, Hackmann K, Porrmann J, Wagner J, Kast K, Wimberger P, Baretton G, Schröck E, Aust D, Klink B
Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples
BMC Cancer 19(1) 2019, 396, DOI Link
Seifert M, Peitzsch C, Gorodetska I, Börner C, Klink B, Dubrovska A
Network-based analysis of prostate cancer cell lines reveals novel marker gene candidates associated with radioresistance and patient relapse
PLoS computational biology 15(11) 2019, e1007460, DOI Link
Biedermann J, Preussler M, Conde M, Peitzsch M, Richter S, Wiedemuth R, Abou-El-Ardat K, Krüger A, Meinhardt M, Schackert G, Leenders WP, Herold-Mende C, Niclou SP, Bjerkvig R, Eisenhofer G, Temme A, Seifert M, Kunz-Schughart LA, Schröck E, Klink B
Mutant IDH1 Differently Affects Redox State and Metabolism in Glial Cells of Normal and Tumor Origin
Cancers 11(12) 2019, DOI Link
Kolbe E, Aleithe S, Rennert C, Spormann L, Ott F, Meierhofer D, Gajowski R, Stöpel C, Hoehme S, Kücken M, Brusch L, Seifert M, von Schoenfels W, Schafmayer C, Brosch M, Hofmann U, Damm G, Seehofer D, Hampe J, Gebhardt R, Matz-Soja M
Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human.
Cell reports 29(13) 2019, 4553-4567.e7, DOI Link
2018
Klapproth E, Dickreuter E, Zakrzewski F, Seifert M, Petzold A, Dahl A, Schröck E, Klink B, Cordes N
Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition
Oncotarget, 2018, 1-16, DOI Link
Lauber C, Klink B, Seifert M
Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroups
BMC Cancer 18, 2018, 399, DOI Link
Mäder L, Blank AE, Capper D, Jansong J, Baumgarten P, Wirsik NM, Zachskorn C, Ehlers J, Seifert M, Klink B, Liebner S, Niclou S, Naumann U, Harter PN, Mittelbronn M
Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma
Oncotarget 9, 2018, 24041-24053, DOI Link
Gladitz J, Klink B, Seifert M
Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion
Acta Neuropathologica Communications, 2018, DOI Link
2017
Abou-El-Ardat K, Seifert M, Becker K, Eisenreich S, Lehmann M, Hackmann K, Rump A, Meijer G, Carvalho B, Temme A, Schackert G, Schröck E, Krex D, Klink B
Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas.
Neuro Oncol 19(4) 2017, 546-57, DOI Link
Vehlow A, Klapproth E, Storch K, Dickreuter E, Seifert M, Dietrich A, Bütof R, Temme A, Cordes N
Adhesion- and stress-related adaptation of glioma radiochemoresistance is circumvented by beta-1 integrin/JNK co-targeting
Oncotarget, 2017, 1-14, DOI Link
Buder T, Deutsch A, Seifert M, Voss-Böhme A
CellTrans: An R Package to Quantify Stochastic Cell State Transitions
Bioinform Biol Insights 11, 2017, 1-14, DOI Link
Seifert M, Beyer A
regNet: An R package for network-based propagation of gene expression alterations
Bioinformatics btx544, 2017, 1-4, DOI Link
Alfonso JCL, Talkenberger K, Seifert M, Klink B, Hawkins-Daarud A, Swanson KR, Hatzikirou H, Deutsch A
The biology and mathematical modelling of glioma invasion: a review
Journal of The Royal Society Interface 14(136) 2017, DOI Link
2016
Seifert M, Friedrich B, Beyer A
Importance of rare gene copy number alterations for personalized tumor characterization and survival analysis
Genome Biology 17, 2016, 1-25, DOI Link
2015
Seifert M, Garbe M, Friedrich B, Mittelbronn M, Klink B
Comparative transcriptomics reveals similarities and differences between astrocytoma grades.
BMC cancer 15(1) 2015, 952, DOI Link